Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764177 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL7811721 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL7815568 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL4063615 | 0.71 | MEN1 (0.36) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL16086202 | 0.70 | MEN1 (0.45) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL16086483 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL3432074 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL1025910 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL1025912 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HCAR2ATM | |
| SCHEMBL3104104 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028449-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF 1,2-DISUBSTITUTED HEXAHYDROPYRIDAZINE-3-CARBOXYLIC ACIDS AND ESTERS THEREOF | HONEYWELL SPECIALTY CHEMICALS SEELZE GMBH (DE) | 2005-03-31 | — | — | WO | disclosed |