Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811721 | 1.00 | MEN1 (0.40) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL8764177 | 1.00 | MEN1 (0.40) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL6498523 | 0.81 | MEN1 (0.36) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL8249142 | 0.80 | OPRM1 (0.41) | MEN1KMT2ALMNAKCNH2POLB | |
| SCHEMBL16086202 | 0.74 | MEN1 (0.45) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL1025910 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL1025912 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL13738791 | 0.73 | MEN1 (0.44) | MEN1KMT2AALDH1A1ATMHCAR2 | |
| SCHEMBL3934353 | 0.73 | ARG1 (0.34) | — | |
| SCHEMBL16086201 | 0.72 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1ATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-A1 | HYDRAZINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000465-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-06 | — | — | WO | disclosed |