Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.37 |
| ▸ | PPARA | Q07869 | 12/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504833 | 0.88 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL6502621 | 0.87 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL6497309 | 0.85 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL6498650 | 0.83 | EPHX2 (0.40) | PPARGPPARAPPARDPDE4APDE4B | |
| SCHEMBL5552673 | 0.80 | PPARG (0.37) | PPARGPPARAPPARD | |
| SCHEMBL6496883 | 0.80 | PPARA (0.42) | PPARGPPARAPPARD | |
| SCHEMBL5549053 | 0.79 | PPARG (0.35) | PPARGPPARAPPARDTPH1 | |
| SCHEMBL6495624 | 0.78 | PPARG (0.39) | PPARGPPARAPPARD | |
| SCHEMBL5549704 | 0.78 | PPARG (0.38) | PPARGPPARAPPARD | |
| SCHEMBL6495937 | 0.78 | WDR5 (0.40) | PPARGPPARAPPARDPDE4ATPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |