Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.40 |
| ▸ | PPARA | Q07869 | 14/20 | 0.40 |
| ▸ | PPARD | Q03181 | 9/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502621 | 0.92 | PPARG (0.41) | PPARGPPARAPPARDSMN1; SMN2 | |
| SCHEMBL6497309 | 0.90 | PPARG (0.41) | PPARGPPARAPPARDSMN1; SMN2 | |
| SCHEMBL6498647 | 0.88 | PPARG (0.37) | PPARGPPARAPPARD | |
| SCHEMBL5552673 | 0.85 | PPARG (0.37) | PPARGPPARAPPARDALDH1A1GAA | |
| SCHEMBL6496883 | 0.84 | PPARA (0.42) | PPARGPPARAPPARD | |
| SCHEMBL5549053 | 0.84 | PPARG (0.35) | PPARGPPARAPPARDALDH1A1GAA | |
| SCHEMBL6495624 | 0.83 | PPARG (0.39) | PPARGPPARAPPARD | |
| SCHEMBL5549704 | 0.83 | PPARG (0.38) | PPARGPPARAPPARDALDH1A1GAA | |
| SCHEMBL6498698 | 0.82 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL5553471 | 0.81 | PPARG (0.35) | PPARGPPARAPPARDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |