Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871107 | 0.85 | GRM5 (0.48) | DRD2DRD3SCD5SCDEGLN1 | |
| SCHEMBL7021172 | 0.85 | TPSAB1 (0.53) | — | |
| SCHEMBL7018734 | 0.84 | TPSAB1 (0.46) | PARP1NPC1RAB9ACCR5PARP14 | |
| Hydrochloric Acid SCHEMBL4402047 | 0.84 | TPSAB1 (0.52) | — | |
| SCHEMBL1872130 | 0.83 | HPN (0.47) | PARP1NPC1RAB9ACCR5PARP14 | |
| SCHEMBL1870287 | 0.82 | CHRM4 (0.48) | DRD2PARP1 | |
| Hydrochloric Acid SCHEMBL1867557 | 0.82 | HPN (0.46) | PARP1NPC1RAB9ACCR5PARP14 | |
| SCHEMBL6501829 | 0.81 | TPSAB1 (0.42) | PARP1MGLLNPC1RAB9ACCR5 | |
| SCHEMBL6498937 | 0.81 | FASN (0.46) | DRD2DRD3SCD5SCDMGLL | |
| Hydrochloric Acid SCHEMBL7107726 | 0.80 | TPSAB1 (0.41) | PARP1MGLLNPC1RAB9ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | disclosed |