Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988131 | 0.80 | CYP3A4 (0.41) | — | |
| SCHEMBL7427629 | 0.79 | PPM1B (0.35) | — | |
| Hydrochloric Acid SCHEMBL7127605 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL12946742 | 0.77 | EPHX1 (0.39) | CTSSCTSKEPHX1 | |
| SCHEMBL4328796 | 0.76 | TSHR (0.37) | CTSSCTSKEPHX1 | |
| SCHEMBL9744380 | 0.76 | TSHR (0.37) | CTSSCTSKEPHX1 | |
| SCHEMBL647264 | 0.76 | TSHR (0.37) | CTSSCTSKEPHX1 | |
| SCHEMBL2712968 | 0.76 | TSHR (0.37) | CTSSCTSKEPHX1 | |
| SCHEMBL9744375 | 0.76 | TSHR (0.37) | CTSSCTSKEPHX1 | |
| SCHEMBL515526 | 0.75 | ADH1C (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903107-B1 | Serine protease inhibitor | AKZO NOBEL N.V. (NL) | 2005-06-07 | — | — | US | disclosed |
| EP-1123280-A1 | SERINE PROTEASE INHIBITOR | Akzo Nobel N.V. (NL) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024718-A1 | SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2000-05-04 | — | — | WO | disclosed |