SCHEMBL649934

SCHEMBL649934

O=S(=O)(Oc1cccc(-c2cccc(-c3ccccn3)c2)c1)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.44
KAT6A Q92794 4/20 0.43
PTGS2 P35354 1/20 0.41
PDE4A P27815 3/20 0.41
PDE4C Q08493 3/20 0.41
PDE4D Q08499 3/20 0.41
CETP P11597 1/20 0.41
SDHB P21912 1/20 0.41
FFAR1 O14842 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
BLM P54132 1/20 0.40
CYP2A6 P11509 1/20 0.40
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PDK2 Q15119 1/20 0.39
TLR4 O00206 1/20 0.39
TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649550 0.97 GRM5 (0.46) GRM5KAT6APTGS2PDE4APDE4C
SCHEMBL4684800 0.82 PTPN1 (0.47) SDHBADORA2AADORA1
SCHEMBL13416088 0.82 CA1 (0.45) PDE4APDE4CPDE4DSDHBADORA2A
SCHEMBL18388565 0.80 ADORA2A (0.46) PDE4APDE4CPDE4DADORA2AADORA1
SCHEMBL19781138 0.79 PDK2 (0.42) KAT6APTGS2PDE4APDE4CPDE4D
SCHEMBL23956362 0.79 DYRK1A (0.40) SDHBADORA2AADORA1
SCHEMBL1138793 0.79 EPHX1 (0.43) PTGS2PDE4APDE4CPDE4DCETP
SCHEMBL20696597 0.78 CHEK2 (0.41) GRM5KAT6AADORA2AADORA1CYP2A6
SCHEMBL129153 0.78 NPC1 (0.44) PTGS2PDE4APDE4CPDE4DSDHB
SCHEMBL9452745 0.78 CA1 (0.46) PDE4APDE4CPDE4DSDHBADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019649-B Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-06-03 CN claimed
CN-119019649-A Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2024-11-26 CN claimed
CN-117247763-A Low-viscosity high-refractive-index low-hardness organic silicon optical cement 翔实光电科技(昆山)有限公司 2023-12-19 CN claimed
EP-3053954-B1 MODIFIED OLEFIN RESIN LG CHEMICAL LTD (KR) 2023-12-06 EP claimed
CN-114874112-A Surface active monomer containing sodium sulfonate group and preparation method and application thereof 中国科学院理化技术研究所 2022-08-09 CN claimed
EP-3053954-A1 OLEFIN RESIN LG Chem, Ltd. (KR) 2016-08-10 EP claimed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
US-4138411-A RUTHENIUM OR OSMIUM CATALYST RHONE-POULENC S. A. (FR) 1979-02-06 US claimed
EP-4317371-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2026-05-13 EP disclosed
US-12618309-B1 Methods for preventing corrosion in flexible pipe with passivating agents CHEVRON U.S.A. INC. (US) 2026-05-05 US disclosed
US-12441959-B2 Composition containing organic ammonium salt MIYOSHI OIL & FAT CO., LTD. (JP) 2025-10-14 US disclosed
US-12384982-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2025-08-12 US disclosed
CN-119019649-B Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-06-03 CN disclosed
US-5589103-A Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1996-12-31 US disclosed
US-5430117-A Nonconjugated diene-vinyl aromatic-α-olefin interpolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-07-04 US disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed
EP-0634427-A1 Higher alpha-olefin copolymer, process for the preparation of the same, rubber composition comprising the same, and rubber molded product comprising the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-01-18 EP disclosed
EP-0606090-A1 Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1994-07-13 EP disclosed
US-4138411-A RUTHENIUM OR OSMIUM CATALYST RHONE-POULENC S. A. (FR) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441959-B2 Composition containing organic ammonium salt SLC6A15, SLC38A7, SLC6A19 GRM5 2524/4885KAT6A 127/4885PTGS2 4362/4885
US-12618309-B1 Methods for preventing corrosion in flexible pipe with passivating agents TRAM1, C1R, C9 GRM5 4156/4885KAT6A 3070/4885PTGS2 384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.