Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426398 | 0.83 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4KCNH2CYP2D6 | |
| Bromide SCHEMBL10794487 | 0.82 | SLC6A2 (0.44) | SLC6A3SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL23295277 | 0.78 | MAOA (0.65) | MAOAMAOBARPTGIRHPGD | |
| SCHEMBL9263579 | 0.77 | HTT (0.47) | SLC6A3SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL9263569 | 0.77 | HTT (0.47) | SLC6A3SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL9263574 | 0.77 | HTT (0.47) | SLC6A3SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL10797460 | 0.77 | SLC6A2 (0.47) | SLC6A3SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL8028469 | 0.76 | NPBWR1 (0.46) | MAOAMAOBHPGD | |
| SCHEMBL21491120 | 0.75 | MAOA (0.69) | MAOAMAOBAR | |
| SCHEMBL29695938 | 0.75 | MAOA (0.58) | MAOAMAOBARPTGIRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |