Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 17/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897899 | 0.71 | MLYCD (0.53) | MLYCD | |
| SCHEMBL3589385 | 0.70 | MLYCD (0.48) | MLYCD | |
| SCHEMBL647994 | 0.68 | MLYCD (1.00) | MLYCD | |
| SCHEMBL1898629 | 0.67 | MLYCD (1.00) | MLYCD | |
| SCHEMBL16296476 | 0.66 | MLYCD (0.49) | MLYCDKDM4EKMT2A | |
| SCHEMBL29123175 | 0.65 | KDM4E (0.82) | MLYCDKDM4EKMT2A | |
| SCHEMBL1900136 | 0.65 | MLYCD (0.72) | MLYCD | |
| SCHEMBL21437132 | 0.65 | MLYCD (0.51) | MLYCDNR1H3NR1H2KDM4EKMT2A | |
| SCHEMBL16296475 | 0.64 | MLYCD (0.48) | MLYCDNR1H3NR1H2KDM4EKMT2A | |
| SCHEMBL1897897 | 0.64 | MLYCD (0.65) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119819-B2 | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-02-21 | — | — | US | disclosed |