Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.48 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.33 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.33 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770531 | 0.83 | NR1H3 (0.49) | MLYCDPOLQKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL16296476 | 0.82 | MLYCD (0.49) | MLYCDPOLQKDM4EKMT2ACHRM5 | |
| SCHEMBL21437132 | 0.81 | MLYCD (0.51) | MLYCDPOLQKDM4EKMT2ACHRM5 | |
| SCHEMBL2903315 | 0.80 | SMN1; SMN2 (0.38) | MLYCDPOLQSMN1; SMN2NR1H3NR1H2 | |
| SCHEMBL16296469 | 0.77 | POLQ (0.49) | MLYCDPOLQKDM4EKMT2ACHRM5 | |
| SCHEMBL12978252 | 0.76 | MLYCD (0.56) | MLYCDPOLQKDM4EKMT2ANR1H3 | |
| SCHEMBL16883807 | 0.75 | SMN1; SMN2 (0.41) | MLYCDKDM4ESMN1; SMN2NR1H3NR1H2 | |
| SCHEMBL23060418 | 0.74 | ATF1 (0.37) | SMN1; SMN2 | |
| SCHEMBL23060401 | 0.73 | RIPK1 (0.35) | SMN1; SMN2 | |
| SCHEMBL26626027 | 0.73 | ATF1 (0.45) | POLQKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221801-B2 | Inhibitors of histone demethylases | EPITHERAPEUTICS APS (DK) | 2015-12-29 | — | — | US | disclosed |
| US-20140371214-A1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES, INC. | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371214-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM1A, KDM3A | MLYCD 2375/4885POLQ 750/4885KDM4E 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.