Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112343 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL8112340 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1021480 | 0.75 | SLC6A3 (0.68) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1021477 | 0.75 | SLC6A3 (0.68) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7806031 | 0.73 | SLC6A4 (0.80) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL3423701 | 0.72 | SLC6A3 (0.66) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL3062717 | 0.72 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL8107599 | 0.72 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL8107601 | 0.72 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL6498583 | 0.72 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984965-A1 | 8-AZABICYCLO(3,2,1)OCT-2-ENE AND OCTANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACH RECEPTORS | NEUROSEARCH A/S (DK) | 2000-03-15 | — | — | EP | claimed |
| WO-1998054181-A1 | 8-AZABICYCLO(3,2,1)OCT-2-ENE AND OCTANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACH RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | claimed |
| US-6964972-B2 | 8-Azabicyclo(3,2,1)oct-2 ene and octane derivatives as cholinergic ligands at nicotinic ACh receptors | NEUROSEARCH A/S (DK) | 2005-11-15 | — | — | US | disclosed |