Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107601 | 1.00 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 | |
| SCHEMBL3062717 | 0.74 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL7806031 | 0.72 | SLC6A4 (0.80) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL6500396 | 0.72 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL8219478 | 0.71 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HTR6SIGMAR1 | |
| SCHEMBL5829586 | 0.71 | SLC6A4 (0.69) | SLC6A2SLC6A4SLC6A3HTR6SIGMAR1 | |
| SCHEMBL3060287 | 0.70 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 | |
| SCHEMBL6488330 | 0.69 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6488329 | 0.69 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6498586 | 0.68 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |