Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 5/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397389 | 0.80 | QPCT (0.45) | QPCTQPCTLLCKKDRJAK3 | |
| Ammonia Solution, Strong SCHEMBL4399088 | 0.79 | ADORA1 (0.48) | ADORA1LCKKDRJAK3MAPK14 | |
| Ammonia Solution, Strong SCHEMBL6529235 | 0.79 | MAPKAPK2 (0.54) | QPCTQPCTLADORA1ADORA2ARPS6KA3 | |
| Ammonia Solution, Strong SCHEMBL4396798 | 0.79 | ADORA1 (0.42) | ADORA1LCKKDRJAK3MAPK14 | |
| Ammonia Solution, Strong SCHEMBL4401603 | 0.78 | DYRK1A (0.47) | ADORA1LCKKDRJAK3MAPK14 | |
| Ammonia Solution, Strong SCHEMBL6496905 | 0.75 | RPS6KA3 (0.46) | ADORA1LCKKDRJAK3MAPK14 | |
| Ammonia Solution, Strong SCHEMBL6527759 | 0.74 | MAPT (0.46) | ADORA1ADORA2ARPS6KA3KDM4EMAPT | |
| Ammonia Solution, Strong SCHEMBL6500606 | 0.73 | KMT2A (0.48) | ADORA1ADORA2ARPS6KA3KDM4EMAPT | |
| SCHEMBL29781428 | 0.67 | AURKA (0.58) | QPCTQPCTLKDRJAK3ADORA2A | |
| SCHEMBL8634290 | 0.66 | QPCT (0.68) | QPCTQPCTLBRD4CREBBPPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004125-A1 | Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors) | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004125-A1 | Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors) | GSK3B, GSK3A, GSKIP | QPCT 882/4885QPCTL 2873/4885ADORA1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.