Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.49 |
| ▸ | F2 | P00734 | 9/20 | 0.40 |
| ▸ | F9 | P00740 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | F5 | P12259 | 1/20 | 0.40 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073683 | 0.85 | F10 (0.53) | F10F2GRM4 | |
| SCHEMBL7073679 | 0.85 | F10 (0.43) | F10F2GRM4AR | |
| SCHEMBL6501405 | 0.83 | F10 (0.51) | F10 | |
| SCHEMBL6494562 | 0.80 | F10 (0.61) | F10F2F9CTRB1F5 | |
| SCHEMBL6500690 | 0.73 | AR (0.44) | AR | |
| SCHEMBL6491855 | 0.73 | F10 (0.46) | F10F2 | |
| SCHEMBL6493981 | 0.70 | F10 (0.64) | F10F2F9CTRB1F5 | |
| SCHEMBL8357787 | 0.70 | F10 (0.57) | F10F2F9CTRB1F5 | |
| SCHEMBL6502113 | 0.70 | F10 (0.71) | F10F2F9CTRB1F5 | |
| SCHEMBL6501532 | 0.69 | ALDH1A1 (0.39) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949550-B2 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-27 | — | — | US | disclosed |