Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.71 |
| ▸ | F2 | P00734 | 15/20 | 0.71 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.71 |
| ▸ | F9 | P00740 | 3/20 | 0.71 |
| ▸ | F5 | P12259 | 2/20 | 0.71 |
| ▸ | PROC | P04070 | 2/20 | 0.70 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493125 | 0.89 | F10 (0.88) | F10F2CTRB1F9F5 | |
| Razaxaban SCHEMBL677372 | 0.83 | F10 (1.00) | F10F2CTRB1F9F5 | |
| Razaxaban SCHEMBL29376499 | 0.83 | F10 (1.00) | F10F2CTRB1F9F5 | |
| Razaxaban SCHEMBL6885838 | 0.82 | F10 (1.00) | F10F2CTRB1F9F5 | |
| Razaxaban SCHEMBL29456625 | 0.82 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL5380554 | 0.81 | F10 (0.82) | F10F2CTRB1F9F5 | |
| SCHEMBL6493981 | 0.79 | F10 (0.64) | F10F2CTRB1F9F5 | |
| SCHEMBL5376245 | 0.79 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL6503086 | 0.78 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL6197266 | 0.78 | F10 (1.00) | F10F2CTRB1F9F5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288316-A1 | Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists | BIOVITRUM AB (SE) | 2005-12-29 | — | — | US | claimed |
| US-6949550-B2 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-27 | — | — | US | claimed |
| US-20030212054-A1 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-13 | — | — | US | claimed |
| US-20050288316-A1 | Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists | BIOVITRUM AB (SE) | 2005-12-29 | — | — | US | disclosed |
| US-6949550-B2 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-27 | — | — | US | disclosed |
| US-20030212054-A1 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-13 | — | — | US | disclosed |
| WO-2003047520-A2 | SUBSTITUTED AMINO METHYL FACTOR Xa INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212054-A1 | Substituted amino methyl factor Xa inhibitors | F11, F10, F9 | F10 2/4885F2 12/4885CTRB1 739/4885 |
| US-20050288316-A1 | Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists | GHSR, GHRHR, PRLHR | F10 1658/4885F2 2617/4885CTRB1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.