Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573415 | 0.86 | ALDH1A1 (0.64) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL6499815 | 0.83 | TSHR (0.66) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL21533589 | 0.83 | LGMN (0.66) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL21724803 | 0.82 | NOTUM (0.50) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL38658169 | 0.81 | LGMN (0.62) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL9830924 | 0.81 | ALDH1A1 (0.52) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL9831805 | 0.81 | ALDH1A1 (0.58) | MAPTALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL17542826 | 0.81 | LGMN (0.59) | LGMNMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL6528497 | 0.81 | LGMN (0.56) | LGMNMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5913512 | 0.81 | MAPT (0.67) | LGMNMAPTALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |