Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502827 | 0.94 | ALOX5AP (0.41) | BCL2MCL1ALOX5APPIK3C2BPTGER1 | |
| SCHEMBL6501134 | 0.93 | BCL2 (0.47) | BCL2MCL1PIK3C2BMRGPRX4DHODH | |
| SCHEMBL6500552 | 0.90 | MRGPRX4 (0.49) | BCL2MCL1ALOX5APPIK3C2BPTGER1 | |
| SCHEMBL6498230 | 0.89 | ALOX5AP (0.38) | BCL2MCL1ALOX5APPTGER1MRGPRX4 | |
| SCHEMBL6498787 | 0.88 | BCL2 (0.40) | BCL2MCL1ALOX5APPIK3C2BNR4A2 | |
| SCHEMBL6500619 | 0.88 | PIK3C2B (0.42) | BCL2MCL1ALOX5APPIK3C2BDHODH | |
| SCHEMBL6502905 | 0.87 | PIK3C2B (0.41) | BCL2MCL1ALOX5APPIK3C2BDHODH | |
| SCHEMBL6500643 | 0.87 | ALOX5AP (0.40) | BCL2MCL1ALOX5APPIK3C2BPTGER1 | |
| SCHEMBL6487917 | 0.87 | PIK3C2B (0.39) | BCL2MCL1PIK3C2BDHODHAGTR1 | |
| SCHEMBL6491148 | 0.86 | DCTPP1 (0.45) | BCL2MCL1ALOX5APMRGPRX4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | BCL2 774/4885MCL1 806/4885ALOX5AP 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.