Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.73 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.73 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.73 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.73 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.73 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.73 |
| ▸ | PPARA | Q07869 | 19/20 | 0.64 |
| ▸ | PPARD | Q03181 | 8/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501430 | 1.00 | PSEN1 (0.73) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6501421 | 1.00 | PSEN1 (0.73) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6383495 | 0.87 | PSEN1 (0.80) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6380278 | 0.83 | PSEN1 (0.74) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5974242 | 0.83 | PSEN1 (0.73) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6376141 | 0.82 | PSEN1 (0.72) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6376145 | 0.82 | PSEN1 (0.72) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6380273 | 0.78 | PPARA (0.84) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5974323 | 0.78 | PPARA (0.72) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5974097 | 0.78 | PPARA (0.80) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |