Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 6/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 6/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.48 |
| ▸ | CACNG3 | O60359 | 6/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.48 |
| ▸ | CACNB3 | P54284 | 6/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.48 |
| ▸ | CACNG7 | P62955 | 6/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.48 |
| ▸ | CACNG1 | Q06432 | 6/20 | 0.48 |
| ▸ | CACNB2 | Q08289 | 6/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.48 |
| ▸ | CACNA1E | Q15878 | 6/20 | 0.48 |
| ▸ | CACNA2D4 | Q7Z3S7 | 6/20 | 0.48 |
| ▸ | CACNA2D3 | Q8IZS8 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078431 | 0.84 | SMYD3 (0.47) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL20338192 | 0.79 | KDM4E (0.46) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30310866 | 0.79 | KDM4E (0.46) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL31345638 | 0.77 | KDM4E (0.46) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL26617997 | 0.77 | KDM4E (0.46) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL16115042 | 0.77 | ACHE (0.48) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30076551 | 0.77 | MAPT (0.44) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7382700 | 0.77 | ACHE (0.43) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL20338237 | 0.77 | MAPT (0.44) | ACHECACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL6492773 | 0.76 | POLB (0.48) | ACHEKDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020644-A1 | Bicyclic fused pyridinyl amides and advantagesous compositons thereof for use as fungicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1485372-A2 | BICYCLIC FUSED PYRIDINYL AMIDES AND ADVANTAGEOUS COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080596-A2 | BICYCLIC FUSED PYRIDINYL AMIDES AND ADVANTAGEOUS COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020644-A1 | Bicyclic fused pyridinyl amides and advantagesous compositons thereof for use as fungicides | CBR3, CBR1, PNPO | ACHE 1366/4885CACNB4 2734/4885CACNA1A 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.