Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795106 | 0.77 | ALDH1A1 (0.48) | POLBL3MBTL1TDP1RECQLCASP6 | |
| SCHEMBL6501518 | 0.76 | ACHE (0.48) | POLBL3MBTL1TDP1RECQLMAPK1 | |
| SCHEMBL3884942 | 0.73 | ACHE (0.56) | MAPK1NSD2ALDH1A1TSHRKDM4E | |
| SCHEMBL13982927 | 0.71 | POLB (0.44) | POLBL3MBTL1TDP1RECQLCASP6 | |
| SCHEMBL2708394 | 0.71 | ACHE (0.56) | MAPK1NSD2ALDH1A1TSHRKDM4E | |
| SCHEMBL30681950 | 0.71 | TDP1 (0.38) | POLBL3MBTL1TDP1RECQLCASP6 | |
| SCHEMBL24581755 | 0.70 | POLB (0.44) | POLBL3MBTL1TDP1RECQLCASP6 | |
| SCHEMBL31266784 | 0.70 | POLB (0.41) | POLBL3MBTL1TDP1RECQLCASP6 | |
| SCHEMBL29056878 | 0.70 | POLB (0.48) | POLBL3MBTL1TDP1RECQLCASP6 | |
| SCHEMBL6494851 | 0.70 | MAPK1 (0.43) | L3MBTL1RECQLMAPK1NSD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020644-A1 | Bicyclic fused pyridinyl amides and advantagesous compositons thereof for use as fungicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020644-A1 | Bicyclic fused pyridinyl amides and advantagesous compositons thereof for use as fungicides | CBR3, CBR1, PNPO | POLB 2598/4885L3MBTL1 1274/4885TDP1 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.