Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PAICS | P22234 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943237 | 0.83 | TDO2 (0.48) | SLC6A4ROCK1IKBKBPAICSTDO2 | |
| Hydrochloric Acid SCHEMBL942643 | 0.81 | TDO2 (0.47) | SLC6A4ROCK1IKBKBPAICSTDO2 | |
| Hydrochloric Acid SCHEMBL2779881 | 0.81 | TDO2 (0.47) | SLC6A4ROCK1IKBKBPAICSTDO2 | |
| SCHEMBL13560051 | 0.80 | HTR2C (0.48) | HTR2CHTR2B | |
| SCHEMBL4823398 | 0.80 | HTR2C (0.48) | HTR2CHTR2B | |
| SCHEMBL942585 | 0.80 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3ROCK1IKBKB | |
| SCHEMBL31128128 | 0.80 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3ROCK1IKBKB | |
| Hydrochloric Acid SCHEMBL4107468 | 0.78 | SLC6A2 (0.67) | SLC6A4SLC6A2SLC6A3ROCK1IKBKB | |
| Hydrochloric Acid SCHEMBL31381194 | 0.78 | SLC6A2 (0.67) | SLC6A4SLC6A2SLC6A3ROCK1IKBKB | |
| Hydrochloric Acid SCHEMBL28674299 | 0.78 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113297-A9 | AZA-RING DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2005-11-24 | — | — | WO | claimed |