SCHEMBL942585

SCHEMBL942585

Clc1ccc(OC2CCNCC2)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.69
SLC6A4 P31645 3/20 0.69
SLC6A3 Q01959 3/20 0.69
HRH1 P35367 2/20 0.55
IKBKB O14920 1/20 0.51
ROCK1 Q13464 4/20 0.49
ROCK2 O75116 1/20 0.49
PRKACA P17612 1/20 0.49
PRKCD Q05655 1/20 0.49
PRKG1 Q13976 1/20 0.49
PKN1 Q16512 1/20 0.49
PKN2 Q16513 1/20 0.49
AAK1 Q2M2I8 1/20 0.49
CDC42BPA Q5VT25 1/20 0.49
Q6ZSR9 Q6ZSR9 1/20 0.49
BMP2K Q9NSY1 1/20 0.49
CDC42BPB Q9Y5S2 1/20 0.49
P2RX7 Q99572 1/20 0.48
HRH3 Q9Y5N1 1/20 0.47
FPR2 P25090 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31128128 1.00 SLC6A2 (0.69) SLC6A2SLC6A4SLC6A3HRH1IKBKB
Hydrochloric Acid SCHEMBL4107468 0.98 SLC6A2 (0.67) SLC6A2SLC6A4SLC6A3HRH1IKBKB
Hydrochloric Acid SCHEMBL31381194 0.98 SLC6A2 (0.67) SLC6A2SLC6A4SLC6A3HRH1IKBKB
SCHEMBL5468103 0.94 SLC6A2 (0.61) SLC6A2SLC6A4SLC6A3HRH1IKBKB
Hydrochloric Acid SCHEMBL5461807 0.92 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3HRH1IKBKB
SCHEMBL6219350 0.90 SLC6A2 (0.75) SLC6A2SLC6A4SLC6A3ROCK1PRKCZ
Hydrochloric Acid SCHEMBL10605496 0.88 SLC6A2 (0.73) SLC6A2SLC6A4SLC6A3ROCK1PRKCZ
Trifluoroacetic Acid SCHEMBL4715454 0.86 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3HRH1ROCK1
SCHEMBL4036160 0.85 HRH1 (0.56) SLC6A2SLC6A4SLC6A3HRH1HRH3
SCHEMBL3121620 0.85 HRH1 (0.50) SLC6A2SLC6A4SLC6A3HRH1IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112071931-A Preparation method of solar cell back panel film for street lamp 江苏斯洛尔集团有限公司 2020-12-11 CN claimed
CN-109244164-B Preparation method of anti-ultraviolet-aging solar cell back panel film 温岭市中天自动化设备有限公司 2020-07-10 CN claimed
CN-107221573-B Anti-ultraviolet-aging solar cell back panel film and preparation method thereof 浙江帝恒实业有限公司 2019-06-21 CN claimed
CN-107221573-A Anti-ultraviolet-aging solar cell back panel film and preparation method thereof 浙江帝恒实业有限公司 2017-09-29 CN claimed
US-20070021404-A1 Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors NEUROSEARCH A/S (DK) 2007-01-25 US claimed
US-20050107428-A1 Chemical compounds ASTRAZENECA AB (SE) 2005-05-19 US claimed
EP-1478624-A1 CHEMICAL COMPOUNDS AstraZeneca AB (SE) 2004-11-24 EP claimed
WO-2003068743-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2003-08-21 WO claimed
EP-4553068-A1 PYRIMIDINE DERIVATIVES ASKA Pharmaceutical Co., Ltd. (JP) 2025-05-14 EP disclosed
WO-2023107547-A2 AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed
WO-2023107547-A2 AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed
US-20210093618-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2021-04-01 US disclosed
CN-112071931-A Preparation method of solar cell back panel film for street lamp 江苏斯洛尔集团有限公司 2020-12-11 CN disclosed
CN-109244164-B Preparation method of anti-ultraviolet-aging solar cell back panel film 温岭市中天自动化设备有限公司 2020-07-10 CN disclosed
WO-2001092227-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2001-12-06 WO disclosed
WO-2001077101-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2001-10-18 WO disclosed
WO-2001062757-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2001-08-30 WO disclosed
WO-2001062728-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2001-08-30 WO disclosed
WO-2001062729-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2001-08-30 WO disclosed
WO-2000058305-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2000-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107428-A1 Chemical compounds CCR10, CCR3, CXCR5 SLC6A2 2886/4885SLC6A4 2650/4885SLC6A3 2949/4885
US-20070021404-A1 Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors SLC18A2, SLC6A2, SLC18A3 SLC6A2 2/4885SLC6A4 5/4885SLC6A3 4/4885
US-20210093618-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF BRIX1, RDX, SULT2A1 SLC6A2 1283/4885SLC6A4 1222/4885SLC6A3 1320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.