Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPRB | P23467 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501851 | 1.00 | MMP8 (0.42) | MMP8CA1CA2CA9CA12 | |
| SCHEMBL6507111 | 0.86 | MMP8 (0.39) | MMP8CA1CA2PTPN1PTPRB | |
| SCHEMBL6507108 | 0.86 | MMP8 (0.39) | MMP8CA1CA2PTPN1PTPRB | |
| SCHEMBL6506768 | 0.84 | ESR1 (0.42) | MMP8CA1CA2CA9CA12 | |
| SCHEMBL6506766 | 0.84 | ESR1 (0.42) | MMP8CA1CA2CA9CA12 | |
| SCHEMBL6509010 | 0.84 | ESR1 (0.40) | MMP8CA1CA2PTPRBBLM | |
| SCHEMBL6514361 | 0.77 | ESR1 (0.48) | MMP8CA1CA2CA9CA12 | |
| SCHEMBL9691089 | 0.74 | MMP8 (0.56) | MMP8PTPN1PTPRBPTPN2PTPRA | |
| SCHEMBL6117630 | 0.73 | MMP8 (0.56) | MMP8PTPN1PTPRBPTPN2PTPRA | |
| SCHEMBL12057080 | 0.72 | NPC1 (0.45) | PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |