Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507108 | 1.00 | MMP8 (0.39) | MMP8BLMESR1ESR2MEN1 | |
| SCHEMBL6509010 | 0.90 | ESR1 (0.40) | MMP8BLMESR1ESR2MEN1 | |
| SCHEMBL6506768 | 0.88 | ESR1 (0.42) | MMP8BLMESR1ESR2MEN1 | |
| SCHEMBL6506766 | 0.88 | ESR1 (0.42) | MMP8BLMESR1ESR2MEN1 | |
| SCHEMBL6501851 | 0.86 | MMP8 (0.42) | MMP8BLMMEN1KMT2APTPRB | |
| SCHEMBL6501855 | 0.86 | MMP8 (0.42) | MMP8BLMMEN1KMT2APTPRB | |
| SCHEMBL6514361 | 0.80 | ESR1 (0.48) | MMP8BLMESR1ESR2MEN1 | |
| SCHEMBL3665931 | 0.72 | ESR1 (0.53) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL9285117 | 0.69 | BLM (0.53) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL503526 | 0.69 | BLM (0.67) | BLMESR1ESR2MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |