Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 4/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502231 | 0.86 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 | |
| SCHEMBL22826421 | 0.85 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 | |
| SCHEMBL14653527 | 0.83 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1LMNAATR | |
| SCHEMBL6502716 | 0.81 | KMT2A (0.42) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 | |
| SCHEMBL24977637 | 0.78 | TDP1 (0.38) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 | |
| SCHEMBL20382691 | 0.77 | SMYD3 (0.38) | CYP4F2CYP4A11ALDH1A1TSHRHSD17B10 | |
| SCHEMBL26638900 | 0.76 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 | |
| SCHEMBL20408354 | 0.75 | KMT2A (0.40) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 | |
| SCHEMBL18587281 | 0.74 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1HSD17B10LMNA | |
| SCHEMBL26639009 | 0.74 | ALDH1A1 (0.35) | CYP4F2CYP4A11ALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176775-A1 | Substituted pyridinones | PHARMACIA CORPORATION | 2005-08-11 | — | — | US | disclosed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176775-A1 | Substituted pyridinones | MAPK1, MAPK6, MAP3K6 | CYP4F2 816/4885CYP4A11 880/4885ALDH1A1 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.