Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180312 | 0.95 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL18673 | 0.87 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL118235 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL20624816 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL10621326 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL2926392 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL28434793 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL4941879 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL28600680 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 | |
| SCHEMBL10621313 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | TRINE PHARMACEUTICALS, INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1389463-A1 | MEDICINE FOR INHIBITING DRUG ELIMINATION PUMP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | ABCB11, ATP6AP1, HRH2 | ALDH1A1 1997/4885MAPK1 1239/4885L3MBTL1 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.