Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492358 | 0.97 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1FAAHPDE3BPDE3A | |
| SCHEMBL6491561 | 0.92 | PLA2G4B (0.40) | CYSLTR2CYSLTR1PLA2G2APPARGTHRA | |
| SCHEMBL6489614 | 0.89 | PLA2G4B (0.41) | CYSLTR2CYSLTR1PPARGTHRATHRB | |
| SCHEMBL6489555 | 0.88 | PLA2G4B (0.45) | CYSLTR2PLA2G2APPARGALOX5AP | |
| SCHEMBL6490815 | 0.87 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1FAAHPDE3BPDE3A | |
| SCHEMBL6497754 | 0.85 | PDE3B (0.44) | CYSLTR2CYSLTR1PDE3BPDE3AP2RY12 | |
| SCHEMBL6497461 | 0.85 | PPARG (0.49) | CYSLTR2CYSLTR1PDE3BPDE3AP2RY12 | |
| SCHEMBL6925454 | 0.85 | PSEN1 (0.41) | KDM4EALDH1A1PLA2G2APPARGALOX5AP | |
| SCHEMBL7194187 | 0.85 | PPARG (0.40) | KDM4EPLA2G2APPARGALOX5APTHRB | |
| SCHEMBL7200184 | 0.85 | PPARG (0.39) | KDM4EPLA2G2APPARGALOX5APTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | CYSLTR2 2679/4885CYSLTR1 2525/4885FAAH 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.