Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489614 | 0.97 | PLA2G4B (0.41) | PLA2G4BCYSLTR2CYSLTR1PPARGTHRB | |
| SCHEMBL6489555 | 0.93 | PLA2G4B (0.45) | PLA2G4BCYSLTR2PPARGFFAR1PLA2G2A | |
| SCHEMBL6502076 | 0.92 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1PPARGPLA2G2ATHRB | |
| SCHEMBL6492358 | 0.89 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1PPARGPLA2G2ATHRB | |
| SCHEMBL7200188 | 0.88 | PPARG (0.38) | PLA2G4BCYSLTR2CYSLTR1PPARGTHRB | |
| SCHEMBL7200184 | 0.88 | PPARG (0.39) | PLA2G4BPPARGPLA2G2ATHRBPPARA | |
| SCHEMBL7194187 | 0.88 | PPARG (0.40) | PLA2G4BPPARGPLA2G2ATHRBPPARA | |
| SCHEMBL6487667 | 0.86 | PLA2G2A (0.40) | PPARGFFAR1FFAR4PLA2G2A | |
| SCHEMBL6925454 | 0.85 | PSEN1 (0.41) | PLA2G4BPPARGPLA2G2ATHRBTHRA | |
| SCHEMBL6501485 | 0.85 | PPARG (0.45) | PLA2G4BPPARGFFAR1FFAR4PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PLA2G4B 4461/4885CYSLTR2 2679/4885CYSLTR1 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.