Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.63 |
| ▸ | CASP6 | P55212 | 19/20 | 0.63 |
| ▸ | CASP8 | Q14790 | 19/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361925 | 0.79 | CASP3 (0.69) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL13146672 | 0.78 | CASP3 (0.67) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL7201965 | 0.77 | CASP3 (0.77) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL18678078 | 0.76 | CASP3 (0.76) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL5495125 | 0.76 | CASP3 (0.69) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL22908216 | 0.76 | CASP3 (0.64) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL17264147 | 0.76 | CASP3 (1.00) | CASP3CASP6CASP8 | |
| SCHEMBL23957238 | 0.75 | CASP3 (0.63) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL7199250 | 0.75 | CASP3 (0.77) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL23957207 | 0.75 | CASP3 (0.63) | CASP3CASP6CASP8CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035497-A1 | CASPASE INHIBITOR COMPRISING 2-ALKYL-4-OXOBUTANOYL GROUP AND PHARMACEUTICAL COMPOSITION THEREOF | LG LIFE SCIENCES LTD. (KR) | 2005-04-21 | — | — | WO | claimed |
| WO-2005035497-A1 | CASPASE INHIBITOR COMPRISING 2-ALKYL-4-OXOBUTANOYL GROUP AND PHARMACEUTICAL COMPOSITION THEREOF | LG LIFE SCIENCES LTD. (KR) | 2005-04-21 | — | — | WO | disclosed |