Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.69 |
| ▸ | CASP6 | P55212 | 18/20 | 0.69 |
| ▸ | CASP8 | Q14790 | 18/20 | 0.69 |
| ▸ | CASP7 | P55210 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13146672 | 0.87 | CASP3 (0.67) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL22908216 | 0.84 | CASP3 (0.64) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL18678078 | 0.82 | CASP3 (0.76) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL20750690 | 0.82 | CASP3 (0.64) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL18850682 | 0.82 | CASP3 (0.69) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL31325781 | 0.81 | CASP3 (0.57) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL18850681 | 0.81 | CASP3 (0.68) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL6502301 | 0.79 | CASP3 (0.63) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL25985226 | 0.79 | KDM4E (0.52) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL17264153 | 0.78 | CASP3 (0.83) | CASP3CASP6CASP8CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174589-A1 | METHOD FOR PREPARING CASPASE INHIBITOR | 正大天晴药业集团股份有限公司 | 2019-09-19 | — | — | WO | disclosed |