Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529233 | 0.86 | S1PR1 (0.41) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6529533 | 0.85 | S1PR1 (0.56) | RARBRARAS1PR1S1PR3S1PR4 | |
| SCHEMBL6529691 | 0.84 | SLC13A5 (0.43) | RARBRARAS1PR1S1PR3S1PR4 | |
| SCHEMBL6530994 | 0.83 | S1PR1 (0.43) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6528237 | 0.82 | S1PR1 (0.57) | RARBRARAS1PR1S1PR3S1PR4 | |
| SCHEMBL6530516 | 0.82 | SLC13A5 (0.53) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6529754 | 0.82 | ESR1 (0.38) | RARBS1PR1 | |
| SCHEMBL6529918 | 0.78 | SLC13A5 (0.45) | — | |
| SCHEMBL6500002 | 0.78 | S1PR1 (0.41) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL6529144 | 0.77 | S1PR1 (0.45) | RARBS1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |