Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529533 | 0.80 | S1PR1 (0.56) | PPARDS1PR1RARB | |
| SCHEMBL6529233 | 0.80 | S1PR1 (0.41) | MEN1KMT2AS1PR1RARBTHRA | |
| SCHEMBL6527585 | 0.80 | S1PR1 (0.39) | S1PR1RARB | |
| SCHEMBL6500002 | 0.77 | S1PR1 (0.41) | S1PR1FFAR1 | |
| SCHEMBL6532174 | 0.77 | PDE4A (0.45) | S1PR1 | |
| SCHEMBL6529144 | 0.76 | S1PR1 (0.45) | S1PR1FFAR1RARB | |
| SCHEMBL6506651 | 0.75 | S1PR1 (0.45) | S1PR1THRATHRB | |
| SCHEMBL6530516 | 0.75 | SLC13A5 (0.53) | S1PR1 | |
| SCHEMBL6530994 | 0.74 | S1PR1 (0.43) | S1PR1RARB | |
| SCHEMBL6529918 | 0.74 | SLC13A5 (0.45) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |