Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502330 | 0.86 | RARB (0.45) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6532174 | 0.85 | PDE4A (0.45) | S1PR1CNR2S1PR4S1PR3S1PR5 | |
| SCHEMBL6530994 | 0.83 | S1PR1 (0.43) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6529006 | 0.82 | S1PR1 (0.44) | S1PR1CNR1CNR2S1PR4S1PR3 | |
| SCHEMBL6529691 | 0.81 | SLC13A5 (0.43) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6529754 | 0.80 | ESR1 (0.38) | S1PR1RARBMEN1KMT2ATHRA | |
| SCHEMBL6530516 | 0.78 | SLC13A5 (0.53) | S1PR1S1PR4S1PR3S1PR5PLA2G4B | |
| SCHEMBL6530176 | 0.76 | S1PR1 (0.45) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6504731 | 0.75 | S1PR1 (0.47) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6529533 | 0.75 | S1PR1 (0.56) | S1PR1RARBS1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |