Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.60 |
| ▸ | DPP4 | P27487 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210261 | 0.98 | DPP4 (0.62) | SLC6A3SLC6A4SLC6A2DPP4MAOB | |
| SCHEMBL6210983 | 0.95 | DPP4 (0.57) | SLC6A3SLC6A4SLC6A2DPP4MAOB | |
| SCHEMBL13650218 | 0.86 | TACR1 (0.56) | SLC6A3SLC6A4SLC6A2DPP4MAOB | |
| SCHEMBL6209701 | 0.82 | PARP10 (0.52) | SLC6A3SLC6A2MAOBMAOARAB9A | |
| SCHEMBL6494035 | 0.81 | PARP10 (0.54) | SLC6A3SLC6A2MAOBMAOAGAA | |
| Ammonia Solution, Strong SCHEMBL6524528 | 0.81 | MAOB (0.51) | SLC6A3SLC6A2MAOBMAOAGAA | |
| SCHEMBL6209698 | 0.80 | RORC (0.47) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL11896096 | 0.80 | RORC (0.45) | SLC6A3SLC6A2MAOBMAOAGAA | |
| SCHEMBL17072362 | 0.79 | LMNA (0.54) | SLC6A3SLC6A2MAOBMAOAGAA | |
| SCHEMBL10041856 | 0.79 | LMNA (0.54) | SLC6A3SLC6A2MAOBMAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234096-A1 | Tetrahydroisoquinoline derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234096-A1 | Tetrahydroisoquinoline derivatives | PPARD, PPARG, PPARA | SLC6A3 3645/4885SLC6A4 3525/4885SLC6A2 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.