Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771735 | 0.97 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5773388 | 0.88 | TARBP2 (0.48) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL343836 | 0.86 | HTT (0.50) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10668171 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL11384351 | 0.86 | ALDH1A1 (0.48) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5776864 | 0.85 | GAA (0.51) | ALDH1A1SMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL5775490 | 0.84 | ALOX5 (0.52) | ALDH1A1SMN1; SMN2MAPTTP53KDM4E | |
| SCHEMBL5774574 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL13527916 | 0.83 | PTGS1 (0.54) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11382098 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-4243406-A | REDUCING INJURIES TO CROP PLANTS WHEN USING AN ALPHA-HALOACETANILIDE AS A HERBICIDE | MONSANTO COMPANY (US) | 1981-01-06 | — | — | US | disclosed |