Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 14/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CDC7 | O00311 | 1/20 | 0.56 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761297 | 0.87 | ADORA1 (0.59) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL28721843 | 0.83 | DHODH (0.77) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL3580925 | 0.81 | KMT2A (0.78) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL15064976 | 0.81 | MEN1 (1.00) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL27971291 | 0.81 | DHODH (1.00) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL23742099 | 0.80 | DHODH (0.72) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL13944335 | 0.79 | MEN1 (0.73) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7933989 | 0.78 | MEN1 (0.77) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL14345630 | 0.78 | DHODH (0.72) | DHODHMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8823153 | 0.78 | ALDH1A1 (0.75) | DHODHMEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | DHODH 1510/4885MEN1 1456/4885KMT2A 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.