Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499830 | 0.92 | PDE3B (0.49) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL6491891 | 0.88 | PDE3B (0.48) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL6923484 | 0.86 | MCL1 (0.47) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL6491030 | 0.85 | PDE3B (0.46) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL6498708 | 0.85 | MAPK1 (0.48) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL6490931 | 0.80 | PPARA (0.35) | PDE3BPDE3AP2RY12MCL1 | |
| SCHEMBL6492328 | 0.77 | PDE3B (0.46) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL4389091 | 0.72 | BRD4 (0.53) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 | |
| SCHEMBL6487097 | 0.72 | CA12 (0.46) | MAPK1MMP13KDM4EPOLBMAPT | |
| SCHEMBL21533500 | 0.72 | BRD4 (0.64) | PDE3BPDE3AP2RY12CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PDE3B 411/4885PDE3A 733/4885P2RY12 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.