Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.44 |
| ▸ | PDE2A | O00408 | 5/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502479 | 0.86 | PDE3B (0.50) | MCL1PDE3BPDE3AP2RY12TSHR | |
| SCHEMBL6927743 | 0.81 | PPARA (0.39) | MCL1TSHRPPARGPPARADHODH | |
| SCHEMBL6499830 | 0.78 | PDE3B (0.49) | MCL1PDE3BPDE3AP2RY12TSHR | |
| SCHEMBL30939004 | 0.78 | MCL1 (0.43) | MCL1PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL3962137 | 0.77 | DHODH (0.43) | DHODH | |
| SCHEMBL6491891 | 0.74 | PDE3B (0.48) | MCL1PDE3BPDE3AP2RY12TSHR | |
| SCHEMBL6924904 | 0.73 | DHODH (0.39) | PPARGPPARADHODHCYP1A2CYP2D6 | |
| SCHEMBL6926116 | 0.73 | SMN1; SMN2 (0.55) | PPARGPPARADHODH | |
| SCHEMBL3963475 | 0.72 | ALDH1A1 (0.40) | DHODH | |
| SCHEMBL11504186 | 0.72 | MCL1 (0.58) | MCL1TSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |