Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602729 | 0.88 | L3MBTL1 (0.74) | L3MBTL1KDM4ETRPM8ALDH1A1PTGDR2 | |
| SCHEMBL6503373 | 0.87 | L3MBTL1 (0.57) | L3MBTL1KDM4ERAB9AGAATRPM8 | |
| SCHEMBL27500333 | 0.85 | L3MBTL1 (0.56) | L3MBTL1KDM4ERAB9AGAATRPM8 | |
| SCHEMBL5238288 | 0.85 | L3MBTL1 (0.58) | L3MBTL1KDM4EALDH1A1PTGDR2 | |
| SCHEMBL18003085 | 0.84 | L3MBTL1 (0.78) | L3MBTL1KDM4ERAB9AGAATRPM8 | |
| SCHEMBL12875848 | 0.83 | L3MBTL1 (0.56) | L3MBTL1KDM4ETRPM8ALDH1A1PTGDR2 | |
| SCHEMBL5341433 | 0.82 | L3MBTL1 (0.55) | L3MBTL1KDM4EPTGDR2MEN1KMT2A | |
| SCHEMBL3417072 | 0.81 | KDM4E (0.61) | KDM4ERAB9AGAATRPM8ALDH1A1 | |
| SCHEMBL6495707 | 0.80 | L3MBTL1 (0.44) | L3MBTL1KDM4ERAB9AGAAALDH1A1 | |
| SCHEMBL6431720 | 0.77 | L3MBTL1 (0.56) | L3MBTL1KDM4ERAB9AGAATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |