Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502484 | 0.87 | L3MBTL1 (0.58) | L3MBTL1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6602729 | 0.86 | L3MBTL1 (0.74) | L3MBTL1KDM4ESMN1; SMN2POLBPTGDR2 | |
| SCHEMBL27500333 | 0.84 | L3MBTL1 (0.56) | L3MBTL1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6502591 | 0.84 | L3MBTL1 (0.47) | L3MBTL1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5238288 | 0.84 | L3MBTL1 (0.58) | L3MBTL1KDM4EPTGDR2ALDH1A1HPGD | |
| SCHEMBL5341433 | 0.81 | L3MBTL1 (0.55) | L3MBTL1KDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL6496085 | 0.80 | KDM4E (0.63) | KDM4ESMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL18173855 | 0.79 | KDM4E (0.51) | L3MBTL1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6495873 | 0.77 | ALDH1A1 (0.55) | L3MBTL1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5192550 | 0.77 | KDM4E (0.55) | L3MBTL1KDM4ESMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |