Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.78 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.78 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.77 |
| ▸ | TUBB | P07437 | 2/20 | 0.77 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.77 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.77 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.77 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.77 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.77 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.77 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.77 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.77 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.77 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.77 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.77 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.77 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.77 |
| ▸ | XDH | P47989 | 3/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29711182 | 1.00 | CYP1A1 (0.78) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Tamarixetin SCHEMBL29750609 | 0.88 | CYP1A2 (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Tamarixetin SCHEMBL30255798 | 0.88 | CYP1A2 (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Tamarixetin SCHEMBL892776 | 0.88 | CYP1A2 (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL31230209 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL15676566 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL1250534 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL30266565 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Water SCHEMBL29154494 | 0.86 | TUBB4A (0.98) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL1229007 | 0.86 | CYP1A1 (0.78) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049589-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA, DIABETES, OBESITY AND SIMILAR DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2005-06-02 | — | — | WO | claimed |
| WO-2005049589-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA, DIABETES, OBESITY AND SIMILAR DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2005-06-02 | — | — | WO | disclosed |