Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.78 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.78 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.77 |
| ▸ | TUBB | P07437 | 2/20 | 0.77 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.77 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.77 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.77 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.77 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.77 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.77 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.77 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.77 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.77 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.77 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.77 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.77 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.77 |
| ▸ | XDH | P47989 | 3/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tamarixetin SCHEMBL892776 | 0.88 | CYP1A2 (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Tamarixetin SCHEMBL30255798 | 0.88 | CYP1A2 (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Tamarixetin SCHEMBL29750609 | 0.88 | CYP1A2 (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL1250534 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL31230209 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL15676566 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL30266565 | 0.87 | TUBB4A (1.00) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL29711182 | 0.86 | CYP1A1 (0.78) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Water SCHEMBL29154494 | 0.86 | TUBB4A (0.98) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL6502620 | 0.86 | CYP1A1 (0.78) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841109-B1 | PRODRUGS OF HYDROXYL-COMPRISING DRUGS | ASCENDIS PHARMA AS (DK) | 2026-04-15 | — | — | EP | disclosed |
| EP-3782649-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2025-05-14 | — | — | EP | disclosed |
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-11786599-B2 | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-17 | — | — | US | disclosed |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | ASCENDIS PHARMA A/S (DK) | 2023-04-20 | — | — | US | disclosed |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | ASCENDIS PHARMA A/S (DE) | 2023-01-24 | — | — | US | disclosed |
| EP-4011396-A1 | RELEASABLE CONJUGATES | QuiaPEG Pharmaceuticals AB (SE) | 2022-06-15 | — | — | EP | disclosed |
| EP-3592393-B1 | RELEASABLE CONJUGATES | QUIAPEG PHARMACEUTICALS AB (SE) | 2021-12-01 | — | — | EP | disclosed |
| US-11116849-B2 | Hydrogel-linked prodrugs releasing tagged drugs | ASCENDIS PHARMA A/S (DK) | 2021-09-14 | — | — | US | disclosed |
| EP-3782649-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | Ascendis Pharma A/S (DK) | 2021-02-24 | — | — | EP | disclosed |
| EP-2741782-A1 | PROTEIN CARRIER-LINKED PRODRUGS | Ascendis Pharma A/S (DK) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013024048-A1 | POLYMERIC HYPERBRANCHED CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |
| WO-2013024049-A1 | PROTEIN CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |
| WO-2013024047-A1 | HIGH-LOADING WATER-SOLUBLE CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |
| US-20130035635-A1 | CARRIER-LINKED CARBAMATE PRODRUG LINKERS | ASCENDIS PHARMA A/S (DK) | 2013-02-07 | — | — | US | disclosed |
| US-20120156259-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | ASCENDIS PHARMA A/S (DK) | 2012-06-21 | — | — | US | disclosed |
| EP-2459220-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | Ascendis Pharma A/S (DK) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011089214-A1 | CARRIER-LINKED CARBAMATE PRODRUG LINKERS | ASCENDIS PHARMA AS (DK) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011012715-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2011-02-03 | — | — | WO | disclosed |
| WO-2005016907-A1 | NOVEL FLAVONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035635-A1 | CARRIER-LINKED CARBAMATE PRODRUG LINKERS | CTSL, SLC16A7, SLC16A8 | CYP1A1 2387/4885CYP1A2 1948/4885CYP1B1 2442/4885 |
| US-20120156259-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | PLG, PHYKPL, PLOD3 | CYP1A1 1878/4885CYP1A2 1645/4885CYP1B1 2005/4885 |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | PLG, PHYKPL, PLOD3 | CYP1A1 1878/4885CYP1A2 1645/4885CYP1B1 2005/4885 |
| US-20230381323-A1 | RELEASABLE CONJUGATES | GUSB, ABCB11, UGT2B7 | CYP1A1 326/4885CYP1A2 185/4885CYP1B1 168/4885 |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | PLG, PHYKPL, PLOD3 | CYP1A1 1878/4885CYP1A2 1645/4885CYP1B1 2005/4885 |
| US-11786599-B2 | Releasable conjugates | GUSB, ABCB11, UGT2B7 | CYP1A1 326/4885CYP1A2 185/4885CYP1B1 168/4885 |
| US-11116849-B2 | Hydrogel-linked prodrugs releasing tagged drugs | PTMS, PGLS, PAM | CYP1A1 601/4885CYP1A2 339/4885CYP1B1 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.