Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949502 | 0.88 | LGMN (0.62) | LGMNMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL655166 | 0.88 | LGMN (0.70) | LGMNMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1573415 | 0.88 | ALDH1A1 (0.64) | LGMNNOTUMMAPTALDH1A1KMT2A | |
| SCHEMBL13896504 | 0.87 | ALDH1A1 (0.69) | LGMNMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL14321489 | 0.87 | LGMN (0.61) | LGMNMAPTALDH1A1KMT2APDK2 | |
| SCHEMBL6502744 | 0.87 | LGMN (0.61) | LGMNMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29838655 | 0.87 | LGMN (0.61) | LGMNMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13722253 | 0.86 | NOTUM (0.64) | LGMNNOTUMMAPTALDH1A1KMT2A | |
| SCHEMBL5913512 | 0.86 | MAPT (0.67) | LGMNMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL24873099 | 0.85 | ALDH1A1 (0.66) | NOTUMMAPTALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |