Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.46 |
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501386 | 0.92 | MCL1 (0.48) | MCL1DCTPP1FFAR4PLA2G2A | |
| SCHEMBL6497177 | 0.92 | DYRK1A (0.42) | MCL1DCTPP1DYRK1ALMNATP53 | |
| SCHEMBL6488344 | 0.91 | MCL1 (0.47) | MCL1FFAR4PLA2G2A | |
| SCHEMBL6490634 | 0.91 | MCL1 (0.46) | MCL1FFAR4LMNAPLA2G2A | |
| SCHEMBL6491512 | 0.90 | MCL1 (0.41) | MCL1DCTPP1LMNATP53MAPT | |
| SCHEMBL6489649 | 0.88 | MCL1 (0.44) | MCL1DCTPP1FFAR4PLA2G2A | |
| SCHEMBL6503536 | 0.88 | MCL1 (0.46) | MCL1DCTPP1FFAR4PLA2G2A | |
| SCHEMBL6489813 | 0.87 | MCL1 (0.43) | MCL1FFAR4PLA2G2A | |
| SCHEMBL6501119 | 0.87 | MCL1 (0.43) | MCL1DCTPP1FFAR4PLA2G2A | |
| SCHEMBL6501595 | 0.85 | MCL1 (0.46) | MCL1DCTPP1FFAR4PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MCL1 806/4885DCTPP1 1534/4885DYRK1A 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.