Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 13/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490596 | 0.91 | MCL1 (0.38) | MCL1PLA2G2ADCTPP1 | |
| SCHEMBL6497679 | 0.90 | MCL1 (0.40) | MCL1PLA2G2AFFAR4BCL2L1DCTPP1 | |
| SCHEMBL6490634 | 0.89 | MCL1 (0.46) | MCL1PLA2G2AFFAR4BCL2L1 | |
| SCHEMBL6502699 | 0.87 | MCL1 (0.46) | MCL1PLA2G2AFFAR4DCTPP1 | |
| SCHEMBL6501386 | 0.86 | MCL1 (0.48) | MCL1PLA2G2AFFAR4DCTPP1 | |
| SCHEMBL6489649 | 0.86 | MCL1 (0.44) | MCL1PLA2G2AFFAR4DCTPP1 | |
| SCHEMBL6503536 | 0.86 | MCL1 (0.46) | MCL1PLA2G2AFFAR4DCTPP1 | |
| SCHEMBL6488344 | 0.86 | MCL1 (0.47) | MCL1PLA2G2AFFAR4 | |
| SCHEMBL6489813 | 0.86 | MCL1 (0.43) | MCL1PLA2G2AFFAR4 | |
| SCHEMBL7171415 | 0.85 | DCTPP1 (0.34) | MCL1DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MCL1 806/4885PLA2G2A 4801/4885FFAR4 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.