Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 4/20 | 0.37 |
| ▸ | FNTB | P49356 | 4/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381218 | 0.84 | FNTA (0.51) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL6503160 | 0.78 | KMT2A (0.50) | KMT2AFNTAFNTBALDH1A1 | |
| SCHEMBL6387223 | 0.74 | FNTA (0.50) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL6384285 | 0.71 | MAOB (0.50) | KMT2ANPC1RAB9AALDH1A1ADRB2 | |
| SCHEMBL6387042 | 0.71 | HSP90AA1 (0.51) | KMT2ANPC1RAB9AALDH1A1ADRB2 | |
| SCHEMBL6757386 | 0.71 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTPOLB | |
| SCHEMBL6503165 | 0.69 | ALDH1A1 (0.37) | KMT2AALDH1A1ADRB2HTTPOLB | |
| SCHEMBL6382326 | 0.68 | FNTA (0.54) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL27584096 | 0.67 | ALDH1A1 (0.60) | KMT2ALTA4HALDH1A1ADRB2HTT | |
| SCHEMBL23638345 | 0.64 | KDM4E (0.60) | LTA4HFNTAFNTBPGGT1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946468-B1 | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors | ZENECA LIMITED (GB) | 2005-09-20 | — | — | US | disclosed |