Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.47 |
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | PPARD | Q03181 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505646 | 0.94 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL6502884 | 0.92 | PPARG (0.43) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL6498808 | 0.92 | PPARA (0.44) | PPARGPPARAPPARDKDM4ERAB9A | |
| SCHEMBL6502624 | 0.90 | PPARG (0.46) | PPARGPPARAPPARDOPRM1OPRD1 | |
| SCHEMBL6507195 | 0.88 | PPARG (0.40) | PPARGPPARAPPARDKDM4ERAB9A | |
| SCHEMBL6504631 | 0.87 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL6495540 | 0.86 | THRB (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6505578 | 0.85 | PPARG (0.41) | PPARGPPARAPPARDOPRM1OPRD1 | |
| SCHEMBL6504638 | 0.85 | PPARA (0.44) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL6497310 | 0.83 | PPARG (0.54) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |