Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328257 | 0.85 | ALOX15 (0.57) | GAAEPHX2PPARGPPARAPPARD | |
| SCHEMBL3948497 | 0.84 | PPARA (0.51) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL3953632 | 0.84 | GAA (0.50) | GAAPPARGPPARAPPARDLDHA | |
| SCHEMBL1906000 | 0.83 | EPHX2 (0.54) | EPHX2PPARGPPARA | |
| SCHEMBL6901178 | 0.83 | EPHX2 (0.54) | EPHX2PPARGPPARA | |
| SCHEMBL1903633 | 0.83 | EPHX2 (0.54) | EPHX2PPARGPPARA | |
| Hydrochloric Acid SCHEMBL3948175 | 0.83 | PPARA (0.50) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL6503458 | 0.83 | PPARA (0.52) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL3945006 | 0.83 | PPARA (0.52) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL6380133 | 0.83 | PPARA (0.55) | EPHX2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |