Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.52 |
| ▸ | PPARD | Q03181 | 10/20 | 0.52 |
| ▸ | PPARG | P37231 | 9/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943600 | 0.88 | PPARA (0.54) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL3948497 | 0.88 | PPARA (0.51) | PPARAPPARDPPARGEPHX2PKM | |
| Hydrochloric Acid SCHEMBL3948175 | 0.87 | PPARA (0.50) | PPARAPPARDPPARGEPHX2PKM | |
| SCHEMBL4328257 | 0.84 | ALOX15 (0.57) | PPARAPPARDPPARGEPHX2ALOX15 | |
| SCHEMBL6503344 | 0.83 | GAA (0.50) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL3945006 | 0.82 | PPARA (0.52) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL6380133 | 0.82 | PPARA (0.55) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL4329462 | 0.81 | ALOX15 (0.44) | PPARAPPARDPPARGPKMALOX15 | |
| SCHEMBL3945079 | 0.81 | EPHX2 (0.47) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL6493866 | 0.79 | PPARA (0.60) | PPARAPPARDPPARGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |