Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843916 | 0.87 | ESR1 (0.59) | ESR1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL2872663 | 0.87 | TDP1 (0.64) | MEN1KMT2ASMN1; SMN2NLRP3NPC1 | |
| SCHEMBL2717444 | 0.85 | ESR1 (0.54) | ESR1MEN1KMT2ANLRP3HPGD | |
| SCHEMBL1549799 | 0.85 | ESR1 (0.61) | ESR1MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28827968 | 0.85 | HPGD (0.62) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL377848 | 0.84 | ESR1 (0.56) | ESR1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL2719391 | 0.84 | ALDH1A1 (0.68) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL5416139 | 0.84 | CYP1A2 (0.68) | ESR1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL3962439 | 0.84 | ESR1 (0.56) | ESR1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL4861445 | 0.84 | MAPK1 (0.57) | ESR1MEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330098-A1 | COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR , AND PREPARATION METHOD AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2011-06-08 | — | — | EP | disclosed |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| US-20050234096-A1 | Tetrahydroisoquinoline derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-20 | — | — | US | disclosed |
| US-20050154042-A1 | N-alkyl pyrroles as HMG-CoA reductase inhibitors | WARNER-LAMBERT COMPANY | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | ESR1 276/4885MEN1 4844/4885KMT2A 3705/4885 |
| US-20050154042-A1 | N-alkyl pyrroles as HMG-CoA reductase inhibitors | HMGCR, DHCR7, CYP11A1 | ESR1 4412/4885MEN1 2624/4885KMT2A 2864/4885 |
| US-20050234096-A1 | Tetrahydroisoquinoline derivatives | PPARD, PPARG, PPARA | ESR1 2387/4885MEN1 4822/4885KMT2A 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.